Thursday, June 9, 2011

Integrin αvβ8 and dendritic cells in airway remodeling

A recent study by Kitamura et al. examined role of αvβ8 integrin in airway inflammation and fibrosis.  This is a complicated study, ranging epithelial cells, macrophages, dendritic cells, and fibroblasts; involving IL-1beta, αvβ8, TGFbeta, latent peptide of TGFbeta, IL-17, IFN-g, chemokines CCL2, CCL20, TLRs; and involving inflammation, DC trafficking, inflammasome, fibrosis/airway remodeling, innate immune, adaptive immune, and epithelia-mesenchymal interactions.



1 comment:

  1. Hello,

    Thank you for sharing such relevant topic with us. Dendritic cells it is a functioning as antigen presenting cells. They can also be found in an immature state in the blood, which are located at various points throughout the dendritic arbor...

    Apoptosis

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