miR-335 in stellate cell activation

An recent study suggested that miR-335 was reduced during hepatic stellate cell activation. Expression of miR-335 inhibited hepatic stellate cell migration and reduced α-SMA and collagen type I. And the authors identified tenascin-C was a target of miR-335.


Reference
[1] Chen C, et al. Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation. Exp Cell Res. 2011 May 7. [Epub ahead of print] PubMed PMID: 21586285.